Inhibition of platelet cyclic AMP phosphodiesterase and platelet aggregation
نویسندگان
چکیده
منابع مشابه
Human Platelet Secretion and Aggregation Induced by Calcium Ionophores Inhibition by PGE and Dibutyryl Cyclic AMP
Ca 2+, Mg2+-ionophores X537A and A23,187 (10-r-10 -6 M) induced the release of adenine nucleotides adenosine diphosphate (ADP, adenosine triphosphate (ATP), serotonin, /3-glucuronidase, Ca 2+, and Mg 2+ from washed human platelets. Enzymes present in the cytoplasm or mitochondria, and Zn 2+ were not released. The rate of ATP and Ca 2+ release measured by firefly lantern extract and murexide dye...
متن کاملHuman platelet secretion and aggregation induced by calcium ionophores. Inhibition by PGE1 and dibutyryl cyclic AMP
Ca2+, Mg2+-ionophores X537A and A23,187 (10(-7)-10(-6) M) induced the release of adenine nucleotides adenosine diphosphate (ADP, adenosine triphosphate (ATP), serotonin, beta-glucuronidase, Ca2+, and Mg2+ from washed human platelets. Enzymes present in the cytoplasm or mitochondria, and Zn2+ were not released. The rate of ATP and Ca2+ release measured by firefly lantern extract and murexide dye...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1974
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)32187-0